正规的买球平台:Dewei Gao



Principal Investigator  Research  Publications  Team


De-Wei Gao (高得伟), Assistant Professor, PI

Address: School of Physical Science and Technology, ShanghaiTech University

Email: gaodw@shanghaitech.edu.cn 

Curriculum Vitae:

2020.9-current, ShanghaiTech University, Assistant Professor, PI

2018.11-2020.9, University of California, Los Angeles (UCLA), Postdoctoral Fellow, Advisor:Prof. Yi Tang

2016.9-2018.10, The Scripps Research Institute (TSRI), Postdoctoral Fellow, Advisor:Prof. Keary Mark Engle                                  

2011.9-2016.7, Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences, Ph.D., Advisor: Prof. Shu-Li You

2007.9-2011.7, Northeast Forestry University, B.S., Advisor: Prof. Jinsong Peng

Honor and Awards:

Shanghai Outstanding Graduate, 2016

SABIC (Saudi Basic Industries Corporation)-CAS (Chinese Academy of Sciences) Scholarship, 2016

National Scholarship for Excellent Ph.D. Students, 2015

NSFC-RSC International Symposium on Emerging Frontiers in Organic Chemistry (Outstanding Poster Prize), 2015

CAS Presidential Scholarship (Excellent Prize), 2014




Our group aims to study selective synthesis of amino acids, peptides and proteins. We are extremely interested in the design of novel catalysts and new catalytic systems. Additionally, our team intends to develop biocompatible reactions, and develop high selectivity reactions for complex peptides and proteins by using photocatalytic strategies.

Postdoctoral Scholars and Research Assistants are available immediately in the Gao group. Please send CV, research summary and list of two references to Prof. Gao by email (gaodw@shanghaitech.edu.cn).




Before joining ShanghaiTech University (Selected Publications):

(1) Gao, D.-W.?; Jamieson, C. S.?; Wang, G.?; Yan, Y.; Zhou, J.; Houk, K. N.; Tang, Y. A Polyketide Cyclase That Forms Medium-Ring Lactones. J. Am. Chem. Soc. 2021, 143, 8084. (?Authors contributed equally)

(2) Gao, D.-W.?; Gao, Y.?; Shao, H.; Qiao, T.-Z.; Wang, X.; Sanchez, B.; Chen, J. S.; Liu, P.; Engle, K. M. Cascade CuH-Catalyzed Conversion of Alkynes to Enantioenriched 1,1-Disubstituted Products. Nat. Catal. 20203, 2329.(?Authors contributed equally).

(3) Gao, D.-W.; Vinogradova, E. V.; Nimmagadda, S. K.; Medina, J. M.; Xiao, Y.; Suciu, R. M.; Cravatt, B. M.; Engle, K. M. Direct Access to Versatile Electrophiles via Catalytic Oxidative Cyanation of Alkenes. J. Am. Chem. Soc2018140, 80698073. (Top 1 “Most Read Article” in June 2018.; Featured in Organic Chemistry Highlights.)

(4) Gao, D.-W.; Xiao, Y.; Liu, M.; Liu, Z.; Karunananda, M. K.; Chen, J. S.; Engle, K. M. Catalytic, Enantioselective Synthesis of Allenyl Boronates. ACS Catal20188, 36503654. (Highlighted in the Jan/Feb ChemRxiv Round-up; Highlighted in Synfacts 2018, 14, 734.; Featured in Organic Chemistry Highlights on October 22, 2018.; One of the “Most Read Articles” in March 2018.)

(5) Gao, D.-W.; Gu, Q.; Zheng, C.; You, S.-L. Synthesis of Planar Chiral Ferrocenes via Transition-Metal-Catalyzed Direct C–H Bond Functionalization. Acc. Chem. Res. 2017, 50, 351–365.

(6) Gao, D.-W.; Gu, Y.; Wang, S.-B.; Gu, Q.; You, S.-L. Pd(0)-Catalyzed Asymmetric C–H Alkenylation for Efficient Synthesis of Planar Chiral Ferrocenes. Organometallics 2016, 35, 3227–3233.

(7) Gao, D.-W.; Gu, Q.; You, S.-L. An Enantioselective Oxidative C?H/C?H Cross-Coupling Reaction: Highly Efficient Method To Prepare Planar Chiral Ferrocenes.J. Am. Chem. Soc. 2016138, 2544–2547. (Highlighted by Chemical & Engineering News on March 14, 2016.)

(8) Gao, D.-W.; Zheng, C.; Gu, Q.; You, S.-L. Pd-Catalyzed Highly Enantioselective Synthesis of Planar Chiral Ferrocenylpyridine Derivatives.Organometallics 2015, 34, 4618–4625.

(9) Gao, D.-W.; Gu, Q.; You, S.-L. Pd(II)-Catalyzed Intermolecular Direct C?H Bond Iodination: An Efficient Approach toward the Synthesis of Axially Chiral Compounds via Kinetic Resolution. ACS Catal20144, 2741–2745. (One of the “Most Read Articles”in July 2014.; Highlighted in ACS Catal. Spotlights.)

(10) Gao, D.-W.; Yin, Q.; Gu, Q.; You, S.-L. Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd(0)-Catalyzed Intramolecular Direct C?H Bond Arylation. J. Am. Chem. Soc. 2014136, 4841–4844. (Highlighted by Synfacts 201410, 597.)

(11) Gao, D.-W.; Shi, Y.-C.; Gu, Q.; Zhao, Z.-L.; You, S.-L. Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-Catalyzed Direct Coupling with Arylboronic Acids.J. Am. Chem. Soc. 2013135, 86–89. (Highlighted by Synfacts 20139, 0417.; Highlighted by Chin. J. Org. Chem201333, 654.)

(12) Nimmagadda, S. K.; Liu, M.; Karunananda, M. K.; Gao, D.-W.; Apolinar, O.; Chen, J. S.; Liu, P.; Engle, K. M. Catalytic, Enantioselective α-Alkylation of Azlactones with Non-Conjugated Alkenes via Directed Nucleopalladation. Angew. Chem. Int. Ed. 201958, 3923–3927.

(13) O’Duill, M. L.; Matsuura, R.; Wang, Y.; Turnbull, J. L.; Gurak Jr, J. A.; Gao, D.-W.; Lu, G.; Liu, P.; Engle, K. M. Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization. J. Am. Chem. Soc. 2017139, 15576–15579.

(14) Wang, J.; Gao, D.-W.; Huang, J.; Tang, S.; Xiong, Z.; Hu, H.; You, S.-L.; Zhu, Q. Palladium-Catalyzed Enantioselective C(sp2)–H Imidoylation by Desymmetrization. ACS Catal. 20177, 3832–3836.

(15) Yin, Q.; Wang, S.-G.; Liang, X.-W.; Gao, D.-W.; Zheng, J.; You, S.-L. Asymmetric Dearomative Chlorination of β-Naphthols. Chem. Sci. 20156, 4179–4183.

(16) Shi, Y.-C.; Yang, R.-F.; Gao, D.-W.; You, S.-L. Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-Catalyzed Annulations with Diarylethynes. Beilstein J. Org. Chem.20139, 1891–1896.

(17) Peng, J.; Zong, C.; Ye, M.; Chen, T.; Gao, D.-W.; Wang, Y.; Chen, C. Direct Transition-Metal-Free Intramolecular C–O Bond Formation: Synthesis of Benzoxazole Derivatives. Org. Biomol. Chem20119, 12251230.


(1) Gao, D.-W.; Zheng, J.; Ye. K.-Y.; Zheng. C.; You, S.-L. Asymmetric Functionalization of C–H Bonds via a Transient Carbon-Metal (C–M) Species. in Asymmetric Functionalization of C–H Bonds, You, S.-L., Ed., Royal Society of Chemistry 2015, pp.141-213.


(1) You, S.-L.; Gao, D.-W.; Gu, Q. A Kind of Planar Chiral Ferrocene Compounds, Synthetic Methods and Their Applications. The Number of Patent (ZL201510757648.8).

(2) You, S.-L.; Gao, D.-W.; Yin, Q.; Gu, Q. The Preparation of Planar Chiral Ferrocene Derivatives and Their Applications. The Number of Patent (ZL201410040306.X).

(3) You, S.-L.; Gu, Q.; Gao, D.-W.; Shi, Y.-C.; Zhao, Z.-L. The Synthesis of New Kind of Planar Chiral Ferrocene Compounds and Their Applications. The Number of  Patent (ZL201210489246.0).



Xia-Min Jiang (蒋夏敏), G1, 2020-current

B.S. in Applied Chemistry, 2016-2020,

Zhejiang Normal University

Xin-Ru Liu (刘欣茹), G1, 2020-current

B.S. in Material Chemistry, 2016-2020,

Shandong Agricultural University